Fundology

ETF · Xtrackers

XSDR Xtrackers MSCI Europe Health Care Screened UCITS ETF-1C- Capitalisation

ISIN LU0292103222London Stock Exchange: XSDRDeutsche Bank AG

Latest close

LSE

£214.45

on

Ongoing charge
0.20% a year
Fund size
£303m

As of , at least 15 min delayed

At a glance

As of 13/11/2026, XSDR (Xtrackers MSCI Europe Health Care Screened UCITS ETF-1C- Capitalisation, ISIN LU0292103222) closed at £214.45 on the London Stock Exchange. Its ongoing charge is 0.20% a year (about £20 on £10,000). Over the five years to 13/11/2026 its total return was +27.4%, or −0.6% after UK CPIH inflation.

Past returns

Total return: the change in the fund’s value with any income reinvested, after its ongoing charges. Periods to .
1 year to 13/11/2026
+10.2%
+6.3% after inflation
3 years to 13/11/2026
+24.1%
+12.1% after inflation
5 years to 13/11/2026
+27.4%
−0.6% after inflation

£1,000 put in five years ago would have been worth about £1,274 on 13/11/2026 — about £994 in today’s spending power, once price rises are taken out. Past performance is not a guide to future returns.

Returns: as reported (delayed data). Inflation: UK CPIH, latest month published.

How we work it out:ReturnsReturns after inflationTotal returnReal returnCPIH

Calendar-year and 12-month returns

Calendar-year returns of Xtrackers SICAV - Xtrackers MSCI Europe Health Care Screened UCITS ETF-1C- Capitalisation in pounds (price, with income reinvested in the fund): 2022 +0.3%, 2023 +6.9%, 2024 +1.1%, 2025 +8.5%; 2026 to 13/11/2026 +9.7%. Returns of Xtrackers SICAV - Xtrackers MSCI Europe Health Care Screened UCITS ETF-1C- Capitalisation in pounds (price, with income reinvested in the fund) over the 12 months to 30/09/2026: 0.0%; to 30/09/2025: −4.6%; to 30/09/2024: +12.1%; to 30/09/2023: +14.4%; to 30/09/2022: +0.9%.

Calendar-year returns of XSDR, in pounds (price, with income reinvested in the fund), to 13/11/2026
YearReturnAfter inflationReturn shown as a bar
to +9.7%+6.2%
to +8.5%+4.8%
to +1.1%−2.4%
+6.9%+2.7%
+0.3%−8.2%
Returns of XSDR over 12-month periods to 30/09/2026, in pounds (price, with income reinvested in the fund)
12 months toReturnAfter inflation
from 0.0%−3.5%
from −4.6%−8.3%
from +12.1%+9.2%
from +14.4%+7.5%
from +0.9%−7.3%

As of , inflation: UK CPIH

How we work it out:Calendar-year returnsWhat a calendar-year return isAccumulating and distributing

Risk: volatility and largest fall

How far the price has swung and fallen. The same record as the returns, in pounds.

Volatility (annualised)

17.1%over 5 years

Volatility, annualised from weekly returns, by period
1 year20.6%
3 years18.2%
5 years17.1%

Annualised from weekly returns. Higher means bumpier.

Largest fall since November 2021
−22.4%
From to
Lowest 12-month return
−19.7%
12 months to
Highest 12-month return
+25.1%
12 months to
Below its highest weekly close since November 2021
0.8%
High of , latest

In words: Volatility of Xtrackers SICAV - Xtrackers MSCI Europe Health Care Screened UCITS ETF-1C- Capitalisation in pounds, annualised from weekly returns to 13/11/2026: 20.6% over 1 year, 18.2% over 3 years, 17.1% over 5 years. Largest fall in the price of Xtrackers SICAV - Xtrackers MSCI Europe Health Care Screened UCITS ETF-1C- Capitalisation since November 2021, in pounds: −22.4% from 30/08/2024 to 11/04/2025. The lowest 12-month return of Xtrackers SICAV - Xtrackers MSCI Europe Health Care Screened UCITS ETF-1C- Capitalisation in pounds (price, with income reinvested in the fund) since January 2021 was −19.7% (12 months to 08/08/2025); the highest was +25.1% (12 months to 08/04/2022). On 13/11/2026 the price of Xtrackers SICAV - Xtrackers MSCI Europe Health Care Screened UCITS ETF-1C- Capitalisation was 0.8% below its highest weekly close since November 2021 (30/08/2024), in pounds.

As of , price, with income reinvested in the fund

How we work it out:Risk figuresFallsVolatilityLargest fall

Charges compared with similar funds

The ongoing charge is taken from the fund’s value every day, so the returns on this page are already after it. Platform and dealing fees are charged separately.
Ongoing charge
0.20%
a year
On £10,000
£20
a year, roughly
Over five years
£100
of £10,000, before growth
Among 29 healthcare funds, share classes counted once
  • 8 charge less
  • 1 the same
  • 19 charge more

Ongoing charge of Xtrackers SICAV - Xtrackers MSCI Europe Health Care Screened UCITS ETF-1C- Capitalisation 0.20% a year. Compared on 14/11/2026, 19 of the 28 other healthcare funds charge more, 1 the same and 8 less (share classes counted once).

As of

A lower charge is not a promise of a higher return: what the fund holds matters more.

Read more:Ongoing charge (OCF)OCF and TERFee dragHow charges add up

In plain English

Xtrackers SICAV - Xtrackers MSCI Europe Health Care Screened UCITS ETF-1C- Capitalisation is an exchange-traded fund (ETF) from Xtrackers, launched in 2007.

It tracks the MSCI Europe Health Care ESG Screened 20-35 Index - EUR — large and medium-sized European companies.

You buy and sell it through a share-dealing account or platform during stock-market hours, like a share.

Its ongoing charge is 0.2% a year — about £20 a year on every £10,000 invested, taken from the fund's value rather than billed to you.

Income from its investments is reinvested inside the fund, so it shows up as a rising price rather than cash paid to you.

Healthcare: Pharmaceutical, biotech and medical-equipment companies.

Terms:ETFIndex fundUCITSAccumulating or incomeShare classISIN

Key facts

Ticker
XSDR
ISIN
LU0292103222
Also listed as
DXSE (Xetra, euros)
Provider
Xtrackers
Tracks
MSCI Europe Health Care ESG Screened 20-35 Index - EUR
Structure
ETF
An exchange-traded fund: bought and sold on the stock exchange through the day, like a share.
Income
Accumulating
Income is reinvested inside the fund, so it shows up as a rising price rather than cash paid to you.
Ongoing charge
0.20% a year · about £20 on £10,000
Fund size
£303m
Launched
Domicile
Luxembourg
UK reporting fund status
Yes — on HMRC’s list of reporting funds (list of )
Reporting fund since . What reporting fund status means
Can usually be held in
ISA and SIPP
Check with your platform: each decides which funds it offers.
Currency hedged
No
Price currency
Pounds (GBP)
Category
Healthcare

Price chart

Closing price
£214.45+10.2% over 1 year · closing price
XSDR closing price: £194.52 on 14/11/2025, £214.45 on 13/11/2026 (+10.2%); low £183.82, high £214.45.

Over the last year, the closing price went from £194.52 on 14/11/2025 to £214.45 on 13/11/2026 (+10.2%). The lowest close shown was £183.82 on 20/03/2026 and the highest £214.45 on 13/11/2026.

One close a week. Before 28/07/2026 the closes are from the weekly price history for this listing; from then on, the closing prices we have recorded. Weeks missing from our record are filled from the same history.

As of , at least 15 min delayed

Five years of prices, and after inflation

262 weekly closes, from 12/11/2021 to 13/11/2026. The same history in November 2026 pounds, adjusted with CPIH inflation.

Create a free account to see the 5-year price chart and the after-inflation chart

Sign-up takes an email address. There is no card to enter and nothing to pay.

How we work it out:Prices and returnsNAV and price

What it holds

As of , XSDR holds 45 positions, according to its published holdings. The largest is Roche at 17.33% of the fund; the ten largest make up 75.6%.
Holdings
43
45 reported in all
Ten largest
75.6%
of the whole fund
Effective number of holdings
11
As concentrated as this many equal-sized holdings (how it is worked out)
Largest holding
17.3%
Roche

Top 10 holdings

Top holdings of XSDR: the ten largest, as a percentage of the whole fund, as of 15/11/2026
Rank#HoldingWeight as a percentage of the fund
1RocheROHealth CareSwitzerland17.33%
2NovartisNOVNHealth CareSwitzerland14.92%
3AstraZenecaAZNHealth CareUnited Kingdom14.13%
4Novo Nordisk · Class BNOVO_BHealth CareDenmark6.66%
5SanofiSANHealth CareFrance5.39%
6GSKGSKHealth CareUnited Kingdom5.16%
7BayerBAYNHealth CareGermany3.12%
8argenxARGXHealth CareNetherlands3.11%
9EssilorLuxotticaELHealth CareFrance2.93%
10Lonza GroupLONNHealth CareSwitzerland2.84%

As of , holdings as published

Where it invests

The portfolio by sector, country and type of asset, as a share of the whole fund. Bonds, cash and positions without a classification are shown as they come, not guessed.

By sector

  1. Health Care99.7%
  2. Other funds0.2%
Added up from the fund’s published holdings, as of 15/11/2026.

By country

  1. Switzerland43.5%
  2. United Kingdom21.9%
  3. France9.5%
  4. Denmark8.9%
  5. Germany7.1%
  6. Netherlands4.8%
  7. Belgium2.3%
  8. Finland0.6%
  9. Other countries1.3%
Added up from the fund’s published holdings, as of 15/11/2026.

By type of asset

  1. Equity99.7%
  2. Cash and money market0.3%
Added up from the fund’s published holdings, as of 15/11/2026.

See the full portfolio

Every holding with search and filters, the whole breakdown by sector, country and type of asset, a map of the 43 largest and what changed since .

All 43 holdings of XSDR

More of the portfolio

The fund publishes 45 holdings; the ten largest make up 75.6% of it. The fund's portfolio is also split by currency.

Create a free account to see the full holdings list and the currency, maturity and credit-quality breakdowns

Sign-up takes an email address. There is no card to enter and nothing to pay.

Holdings:Compare what it holds with another fundHoldings overlapHow overlap is measured

Risk and return in depth

Ratios that weigh return against its ups and downs, every rolling period rather than a few fixed ones, and each large fall with how long it took to recover.
  • Sharpe, Sortino and Calmar ratios

    Sharpe, Sortino and Calmar ratios over 1, 3 and 5 years, from weekly returns in pounds.

    With a free account
  • Rolling returns

    The full range of 254 rolling 12-month returns since January 2021, and of 150 rolling three-year returns, in pounds, with how often they were above zero.

    With a free account
  • Largest falls and recoveries

    The 3 largest falls since November 2021, in pounds, with how many weeks each took to reach its low and to recover.

    With a free account

Create a free account to see the risk ratios, every rolling return and each large fall and its recovery

Sign-up takes an email address. There is no card to enter and nothing to pay.

  • Moves compared with a similar fund

    Correlation and beta of weekly returns in pounds against iShares Core MSCI Europe UCITS ETF EUR (Acc), over the three years to 13/11/2026 (129 weeks).

    Pro

Pro — currently by invitation

Pro includes moves against a comparable fund

Pro is open by invitation while it is being built. There is nothing to buy. To ask about access, email [email protected].

Questions people ask

What is the ongoing charge of XSDR?

The ongoing charge of XSDR is 0.20% a year — about £20 a year on every £10,000 invested, taken from the fund’s value rather than billed to you. Platform and dealing fees are charged separately. Ongoing charge of Xtrackers SICAV - Xtrackers MSCI Europe Health Care Screened UCITS ETF-1C- Capitalisation 0.20% a year. Compared on 14/11/2026, 19 of the 28 other healthcare funds charge more, 1 the same and 8 less (share classes counted once).

What does XSDR track?

XSDR tracks the MSCI Europe Health Care ESG Screened 20-35 Index - EUR — large and medium-sized European companies.

Is XSDR accumulating or distributing?

XSDR is accumulating: income is reinvested inside the fund, so it shows up as a rising price rather than cash paid to you.

What is the ISIN of XSDR?

The ISIN of XSDR is LU0292103222. An ISIN identifies one exact share class of a fund; XSDR is its ticker on the London Stock Exchange. The same share class is also listed as DXSE (Xetra, euros).

What does XSDR hold?

As of 15/11/2026, XSDR holds 45 positions, according to its published holdings. The largest is Roche at 17.33% of the fund; the ten largest make up 75.6%. Its ten largest holdings are Roche (17.33%), Novartis (14.92%), AstraZeneca (14.13%), Novo Nordisk · Class B (6.66%), Sanofi (5.39%), GSK (5.16%), Bayer (3.12%), argenx (3.11%), EssilorLuxottica (2.93%) and Lonza Group (2.84%).

What were XSDR’s returns in each of the last five years?

Calendar-year returns of XSDR in pounds (price, with income reinvested in the fund): 2022 +0.3%, 2023 +6.9%, 2024 +1.1%, 2025 +8.5%; 2026 to 13/11/2026 +9.7%. Past performance is not a guide to future returns.

How has XSDR done after inflation?

Over the five years to 13/11/2026 XSDR’s total return was +27.4%, or −0.6% after UK CPIH inflation. Past performance is not a guide to future returns.

Similar funds

More healthcare funds, largest first. Size is a fact, not a verdict.

Fund documents and methods

Fund documents
Fund page at Xtrackers (DWS) (links checked )

Methodology:ReturnsCategoriesAll methods

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