Fundology

ETF · Xtrackers

XGES MSCI Genomic Healthcare Innov UCITS ETF

ISIN IE000KD0BZ68London Stock Exchange: XGESDeutsche Bank AG

Latest close

LSE

£32.81

on

Ongoing charge
0.36% a year
Fund size
£12.5m

As of , at least 15 min delayed

At a glance

As of 13/11/2026, XGES (MSCI Genomic Healthcare Innov UCITS ETF, ISIN IE000KD0BZ68) closed at £32.81 on the London Stock Exchange. Its ongoing charge is 0.36% a year (about £36 on £10,000). Over the three years to 13/11/2026 its price changed by +59.1%, or +43.7% after UK CPIH inflation.

Past returns

Total return: the change in the fund’s value with any income reinvested, after its ongoing charges. Periods to .
1 year to 13/11/2026
+30.1%
+25.5% after inflation
3 years to 13/11/2026
+59.1%
+43.7% after inflation

Returns: as reported (delayed data) and worked out from recorded daily closes. Inflation: UK CPIH, latest month published.

How we work it out:ReturnsReturns after inflationTotal returnReal returnCPIH

Calendar-year and 12-month returns

Calendar-year returns of Xtrackers IE Plc - MSCI Genomic Healthcare Innov UCITS ETF in pounds (price, with income reinvested in the fund): 2023 −7.9%, 2024 +0.4%, 2025 +9.3%; 2026 to 13/11/2026 +27.1%. Returns of Xtrackers IE Plc - MSCI Genomic Healthcare Innov UCITS ETF in pounds (price, with income reinvested in the fund) over the 12 months to 30/09/2026: +41.0%; to 30/09/2025: +1.5%; to 30/09/2024: +5.3%; to 30/09/2023: −13.9%.

Calendar-year returns of XGES, in pounds (price, with income reinvested in the fund), to 13/11/2026
YearReturnAfter inflationReturn shown as a bar
to +27.1%+23.0%
to +9.3%+5.6%
to +0.4%−3.0%
−7.9%−11.6%
Returns of XGES over 12-month periods to 30/09/2026, in pounds (price, with income reinvested in the fund)
12 months toReturnAfter inflation
from +41.0%+36.0%
from +1.5%−2.5%
from +5.3%+2.6%
from −13.9%−19.0%

As of , inflation: UK CPIH

How we work it out:Calendar-year returnsWhat a calendar-year return isAccumulating and distributing

Risk: volatility and largest fall

How far the price has swung and fallen. The same record as the returns, in pounds.

Volatility (annualised)

19.7%over 3 years

Volatility, annualised from weekly returns, by period
1 year23.7%
3 years19.7%

Annualised from weekly returns. Higher means bumpier.

Largest fall since July 2022
−33.4%
From to
Lowest 12-month return
−23.6%
12 months to
Highest 12-month return
+43.2%
12 months to
Below its highest weekly close since July 2022
2.5%
High of , latest

In words: Volatility of Xtrackers IE Plc - MSCI Genomic Healthcare Innov UCITS ETF in pounds, annualised from weekly returns to 13/11/2026: 23.7% over 1 year, 19.7% over 3 years. Largest fall in the price of Xtrackers IE Plc - MSCI Genomic Healthcare Innov UCITS ETF since July 2022, in pounds: −33.4% from 12/08/2022 to 11/04/2025. The lowest 12-month return of Xtrackers IE Plc - MSCI Genomic Healthcare Innov UCITS ETF in pounds (price, with income reinvested in the fund) since July 2022 was −23.6% (12 months to 10/11/2023); the highest was +43.2% (12 months to 21/08/2026). On 13/11/2026 the price of Xtrackers IE Plc - MSCI Genomic Healthcare Innov UCITS ETF was 2.5% below its highest weekly close since July 2022 (30/10/2026), in pounds.

As of , price, with income reinvested in the fund

How we work it out:Risk figuresFallsVolatilityLargest fall

Charges compared with similar funds

The ongoing charge is taken from the fund’s value every day, so the returns on this page are already after it. Platform and dealing fees are charged separately.
Ongoing charge
0.36%
a year
On £10,000
£36
a year, roughly
Over five years
£179
of £10,000, before growth
Among 29 healthcare funds, share classes counted once
  • 18 charge less
  • 0 the same
  • 10 charge more

Ongoing charge of Xtrackers IE Plc - MSCI Genomic Healthcare Innov UCITS ETF 0.36% a year. Compared on 14/11/2026, 10 of the 28 other healthcare funds charge more, 0 the same and 18 less (share classes counted once).

As of

A lower charge is not a promise of a higher return: what the fund holds matters more.

As of

Read more:Ongoing charge (OCF)OCF and TERFee dragHow charges add up

In plain English

Xtrackers IE Plc - MSCI Genomic Healthcare Innov UCITS ETF is an exchange-traded fund (ETF) from Xtrackers, launched in 2022.

It tracks the MSCI ACWI IMI Genomic Innovation Select ESG Screened 100 Index - Benchmark TR Net — large and medium-sized companies across developed and emerging markets.

You buy and sell it through a share-dealing account or platform during stock-market hours, like a share.

Its ongoing charge is 0.36% a year — about £36 a year on every £10,000 invested, taken from the fund's value rather than billed to you.

Income from its investments is reinvested inside the fund, so it shows up as a rising price rather than cash paid to you.

Healthcare: Pharmaceutical, biotech and medical-equipment companies.

Terms:ETFIndex fundUCITSAccumulating or incomeShare classISIN

Key facts

Ticker
XGES
ISIN
IE000KD0BZ68
Also listed as
XGEN (London Stock Exchange, US dollars)
Provider
Xtrackers
Tracks
MSCI ACWI IMI Genomic Innovation Select ESG Screened 100 Index
Structure
ETF
An exchange-traded fund: bought and sold on the stock exchange through the day, like a share.
Income
Accumulating
Income is reinvested inside the fund, so it shows up as a rising price rather than cash paid to you.
Ongoing charge
0.36% a year · about £36 on £10,000
Fund size
£12.5m
Launched
Domicile
Ireland
UK reporting fund status
Yes — on HMRC’s list of reporting funds (list of )
Reporting fund since . What reporting fund status means
Can usually be held in
ISA and SIPP
Check with your platform: each decides which funds it offers.
Currency hedged
No
Price currency
Pounds (GBP)
Category
Healthcare

Price chart

Closing price
£32.81+26.0% over 1 year · closing price
XGES closing price: £26.03 on 14/11/2025, £32.81 on 13/11/2026 (+26.0%); low £23.62, high £33.67.

Over the last year, the closing price went from £26.03 on 14/11/2025 to £32.81 on 13/11/2026 (+26.1%). The lowest close shown was £23.62 on 01/05/2026 and the highest £33.67 on 30/10/2026.

One close a week. Before 18/09/2026 the closes are from the weekly price history for this listing; from then on, the closing prices we have recorded.

As of , at least 15 min delayed

Five years of prices, and after inflation

225 weekly closes, from 22/07/2022 to 13/11/2026. The same history in November 2026 pounds, adjusted with CPIH inflation.

Create a free account to see the 5-year price chart and the after-inflation chart

Sign-up takes an email address. There is no card to enter and nothing to pay.

How we work it out:Prices and returnsNAV and price

What it holds

As of , XGES holds 104 positions, according to its published holdings. The largest is Moderna at 5.95% of the fund; the ten largest make up 46.7%.
Holdings
100
104 reported in all
Ten largest
46.7%
of the whole fund
Effective number of holdings
32
As concentrated as this many equal-sized holdings (how it is worked out)
Largest holding
6.0%
Moderna

Top 10 holdings

Top holdings of XGES: the ten largest, as a percentage of the whole fund, as of 15/11/2026
Rank#HoldingWeight as a percentage of the fund
1ModernaMRNAHealth CareUnited States5.95%
2Agilent TechnologiesAHealth CareUnited States4.99%
3Lonza GroupLONNHealth CareSwitzerland4.95%
4DanaherDHRHealth CareUnited States4.92%
5IlluminaILMNHealth CareUnited States4.58%
6RocheROHealth CareSwitzerland4.57%
7NateraNTRAHealth CareUnited States4.45%
8Vertex PharmaceuticalsVRTXHealth CareUnited States4.40%
9GSK American Depository Shares RepHealth CareUnited Kingdom4.29%
10argenxARGXHealth CareNetherlands3.61%

As of , holdings as published

Where it invests

The portfolio by sector, country and type of asset, as a share of the whole fund. Bonds, cash and positions without a classification are shown as they come, not guessed.

By country

  1. United States67.4%
  2. Switzerland12.6%
  3. China8.5%
  4. Netherlands5.6%
  5. United Kingdom4.5%
  6. Spain0.4%
  7. Sweden0.3%
  8. Australia0.2%
  9. Other countries0.4%
  10. Not classified0.1%
Added up from the fund’s published holdings, as of 15/11/2026.

By type of asset

  1. Equity99.9%
  2. Cash and money market0.1%
Added up from the fund’s published holdings, as of 15/11/2026.

See the full portfolio

Every holding with search and filters, the whole breakdown by sector, country and type of asset, a map of the 100 largest and what changed since .

All 100 holdings of XGES

More of the portfolio

The fund publishes 104 holdings; the ten largest make up 46.7% of it. The fund's portfolio is also split by currency.

Create a free account to see the full holdings list and the currency, maturity and credit-quality breakdowns

Sign-up takes an email address. There is no card to enter and nothing to pay.

Holdings:Compare what it holds with another fundHoldings overlapHow overlap is measured

Risk and return in depth

Ratios that weigh return against its ups and downs, every rolling period rather than a few fixed ones, and each large fall with how long it took to recover.
  • Sharpe, Sortino and Calmar ratios

    Sharpe, Sortino and Calmar ratios over 1 and 3 years, from weekly returns in pounds.

    With a free account
  • Rolling returns

    The full range of 173 rolling 12-month returns since July 2022, in pounds, with how often they were above zero.

    With a free account
  • Largest falls and recoveries

    The 3 largest falls since July 2022, in pounds, with how many weeks each took to reach its low and to recover.

    With a free account

Create a free account to see the risk ratios, every rolling return and each large fall and its recovery

Sign-up takes an email address. There is no card to enter and nothing to pay.

  • Rank among similar funds

    Rank by total return over 1 year among up to 11 healthcare funds investing globally, not currency-hedged, highest first.

    Pro
  • Moves compared with a similar fund

    Correlation and beta of weekly returns in pounds against iShares Core MSCI World UCITS ETF, over the three years to 13/11/2026 (152 weeks).

    Pro

Pro — currently by invitation

Pro includes the rank among similar funds and moves against a comparable fund

Pro is open by invitation while it is being built. There is nothing to buy. To ask about access, email [email protected].

Questions people ask

What is the ongoing charge of XGES?

The ongoing charge of XGES is 0.36% a year — about £36 a year on every £10,000 invested, taken from the fund’s value rather than billed to you. Platform and dealing fees are charged separately. Ongoing charge of Xtrackers IE Plc - MSCI Genomic Healthcare Innov UCITS ETF 0.36% a year. Compared on 14/11/2026, 10 of the 28 other healthcare funds charge more, 0 the same and 18 less (share classes counted once).

What does XGES track?

XGES tracks the MSCI ACWI IMI Genomic Innovation Select ESG Screened 100 Index - Benchmark TR Net — large and medium-sized companies across developed and emerging markets.

Is XGES accumulating or distributing?

XGES is accumulating: income is reinvested inside the fund, so it shows up as a rising price rather than cash paid to you.

What is the ISIN of XGES?

The ISIN of XGES is IE000KD0BZ68. An ISIN identifies one exact share class of a fund; XGES is its ticker on the London Stock Exchange. The same share class is also listed as XGEN (London Stock Exchange, US dollars).

What does XGES hold?

As of 15/11/2026, XGES holds 104 positions, according to its published holdings. The largest is Moderna at 5.95% of the fund; the ten largest make up 46.7%. Its ten largest holdings are Moderna (5.95%), Agilent Technologies (4.99%), Lonza Group (4.95%), Danaher (4.92%), Illumina (4.58%), Roche (4.57%), Natera (4.45%), Vertex Pharmaceuticals (4.40%), GSK American Depository Shares Rep (4.29%) and argenx (3.61%).

What were XGES’s returns in each of the last five years?

Calendar-year returns of XGES in pounds (price, with income reinvested in the fund): 2023 −7.9%, 2024 +0.4%, 2025 +9.3%; 2026 to 13/11/2026 +27.1%. Past performance is not a guide to future returns.

How has XGES done after inflation?

Over the three years to 13/11/2026 XGES’s price changed by +59.1%, or +43.7% after UK CPIH inflation. Past performance is not a guide to future returns.

Similar funds

More healthcare funds, largest first. Size is a fact, not a verdict.

Fund documents and methods

Fund documents
Fund page at Xtrackers (DWS) (links checked )

Methodology:ReturnsCategoriesAll methods

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