Fundology

Investment trust

RTW RTW Biotech Opportunities Ltd USD

ISIN GG00BKTRRM22London Stock Exchange: RTW

Latest close

LSE

$2.44

on

As of , at least 15 min delayed

At a glance

As of 13/11/2026, RTW (RTW Biotech Opportunities Ltd USD, ISIN GG00BKTRRM22) closed at $2.44 on the London Stock Exchange. Over the five years to 13/11/2026 its price changed by +31.0% (income paid out is not included), or +2.3% after UK CPIH inflation.

Past returns

Change in the fund’s price, after its ongoing charges. Any income paid out is not included. Periods to .
1 year to 13/11/2026
+35.2%
+30.4% after inflation
3 years to 13/11/2026
+103.1%
+83.5% after inflation
5 years to 13/11/2026
+31.0%
+2.3% after inflation

£1,000 put in five years ago would have been worth about £1,310 on 13/11/2026 — about £1,023 in today’s spending power, once price rises are taken out. Past performance is not a guide to future returns.

Returns: worked out from recorded daily closes. Inflation: UK CPIH, latest month published.

How we work it out:ReturnsReturns after inflationTotal returnReal returnCPIH

Calendar-year and 12-month returns

Calendar-year returns of RTW Biotech Opportunities Ltd USD in pounds (price only, income paid out not included): 2022 −23.8%, 2023 +9.6%, 2024 +5.2%, 2025 +39.1%; 2026 to 13/11/2026 +14.3%. Returns of RTW Biotech Opportunities Ltd USD in pounds (price only, income paid out not included) over the 12 months to 30/09/2026: +55.4%; to 30/09/2025: +1.5%; to 30/09/2024: +13.6%; to 30/09/2023: −3.2%; to 30/09/2022: −27.5%.

Calendar-year returns of RTW, in pounds (price only — income paid out is not included), to 13/11/2026
YearReturnAfter inflationReturn shown as a bar
to +14.3%+10.6%
to +39.1%+34.3%
to +5.2%+1.6%
+9.6%+5.3%
−23.8%−30.3%
Returns of RTW over 12-month periods to 30/09/2026, in pounds (price only — income paid out is not included)
12 months toReturnAfter inflation
from +55.4%+49.9%
from +1.5%−2.4%
from +13.6%+10.7%
from −3.2%−9.0%
from −27.5%−33.4%

As of , inflation: UK CPIH

How we work it out:Calendar-year returnsWhat a calendar-year return isAccumulating and distributing

Risk: volatility and largest fall

How far the price has swung and fallen. The same record as the returns, in pounds.

Volatility (annualised)

27.3%over 5 years

Volatility, annualised from weekly returns, by period
1 year23.8%
3 years22.8%
5 years27.3%

Annualised from weekly returns. Higher means bumpier.

Largest fall since November 2021
−39.6%
From to
Lowest 12-month return
−46.2%
12 months to
Highest 12-month return
+106.0%
12 months to
Below its highest weekly close since November 2021
3.2%
High of , latest

In words: Volatility of RTW Biotech Opportunities Ltd USD in pounds, annualised from weekly returns to 13/11/2026: 23.8% over 1 year, 22.8% over 3 years, 27.3% over 5 years. Largest fall in the price of RTW Biotech Opportunities Ltd USD since November 2021, in pounds: −39.6% from 31/12/2021 to 07/04/2023. The lowest 12-month return of RTW Biotech Opportunities Ltd USD in pounds (price only, income paid out not included) since January 2021 was −46.2% (12 months to 01/07/2022); the highest was +106.0% (12 months to 03/07/2026). On 13/11/2026 the price of RTW Biotech Opportunities Ltd USD was 3.2% below its highest weekly close since November 2021 (14/08/2026), in pounds.

As of , price only — income paid out is not included

How we work it out:Risk figuresFallsVolatilityLargest fall

In plain English

RTW Biotech Opportunities Ltd USD is an investment trust.

You buy and sell it through a share-dealing account or platform during stock-market hours, like a share.

Investment trusts: Companies on the stock exchange that invest in other assets. Their share price can be above or below the value of what they own.

Terms:Investment trustShare classISIN

Key facts

Ticker
RTW
ISIN
GG00BKTRRM22
Structure
Investment trust
A company listed on the stock exchange that invests in other assets; its price can differ from the value of what it holds.
Domicile
Guernsey
Can usually be held in
ISA and SIPP
Check with your platform: each decides which funds it offers.
Currency hedged
No
Price currency
USD

Price chart

Closing price
$2.44+31.9% over 1 year · closing price
RTW closing price: $1.85 on 14/11/2025, $2.44 on 13/11/2026 (+31.9%); low $1.85, high $2.58.

Over the last year, the closing price went from $1.85 on 14/11/2025 to $2.44 on 13/11/2026 (+32.2%). The lowest close shown was $1.85 on 14/11/2025 and the highest $2.58 on 14/08/2026.

One close a week. Before 31/07/2026 the closes are from the weekly price history for this listing; from then on, the closing prices we have recorded. Price only — income paid out is not included.

As of , at least 15 min delayed

Five years of prices, and after inflation

262 weekly closes, from 12/11/2021 to 13/11/2026. The same history in November 2026 pounds, adjusted with CPIH inflation.

Create a free account to see the 5-year price chart and the after-inflation chart

Sign-up takes an email address. There is no card to enter and nothing to pay.

How we work it out:Prices and returnsNAV and price

Risk and return in depth

Ratios that weigh return against its ups and downs, every rolling period rather than a few fixed ones, and each large fall with how long it took to recover.
  • Sharpe, Sortino and Calmar ratios

    Sharpe, Sortino and Calmar ratios over 1, 3 and 5 years, from weekly returns in pounds.

    With a free account
  • Rolling returns

    The full range of 254 rolling 12-month returns since January 2021, and of 150 rolling three-year returns, in pounds, with how often they were above zero.

    With a free account
  • Largest falls and recoveries

    The 3 largest falls since November 2021, in pounds, with how many weeks each took to reach its low and to recover.

    With a free account

Create a free account to see the risk ratios, every rolling return and each large fall and its recovery

Sign-up takes an email address. There is no card to enter and nothing to pay.

  • Moves compared with a similar fund

    Correlation and beta of weekly returns in pounds against iShares Core MSCI World UCITS ETF, over the three years to 13/11/2026 (154 weeks).

    Pro

Pro — currently by invitation

Pro includes moves against a comparable fund

Pro is open by invitation while it is being built. There is nothing to buy. To ask about access, email [email protected].

Questions people ask

What is the ISIN of RTW?

The ISIN of RTW is GG00BKTRRM22. An ISIN identifies one exact share class of a fund; RTW is its ticker on the London Stock Exchange.

What were RTW’s returns in each of the last five years?

Calendar-year returns of RTW in pounds (price only, income paid out not included): 2022 −23.8%, 2023 +9.6%, 2024 +5.2%, 2025 +39.1%; 2026 to 13/11/2026 +14.3%. Past performance is not a guide to future returns.

How has RTW done after inflation?

Over the five years to 13/11/2026 RTW’s price changed by +31.0% (income paid out is not included), or +2.3% after UK CPIH inflation. Past performance is not a guide to future returns.

Similar funds

More investment trusts, largest first. Size is a fact, not a verdict.

Fund documents and methods

Methodology:ReturnsCategoriesAll methods

A machine-readable copy of this page: Markdown.